Traceability to Absorbed-dose-to-water Primary Standards in Dosimetry of Brachytherapy Sources Used for Radiotherapy

نویسندگان

  • Maurizio Bovi
  • Maria Pia Toni
  • Isabelle Aubineau-Lanièce
  • Jean-Marc Bordy
  • João Cardoso
  • Bruno Chauvenet
  • Frantisek Gabris
  • Jan-Erik Grindborg
  • Antonio Stefano Guerra
  • Antti Kosunen
  • Carlos Oliveira
  • Maria Pimpinella
  • Thorsten Sander
  • Hans-Joachim Selbach
  • Vladimír Sochor
  • Jaroslav Šolc
  • Jacco de Pooter
  • Eduard van Dijk
چکیده

− In the current brachytherapy practice, the procedures to determine the absorbed dose imparted to the patient are affected by an uncertainty higher than in radiotherapy with external beams. That could reduce the success of brachytherapy treatments. Most of the uncertainty is due to a lacking metrology: no absorbed-dose primary standards are so far available to assure direct traceability in dosimetry of brachytherapy sources. This paper outlines the project “Increasing cancer treatment efficacy using 3D brachytherapy”, co-funded in the framework of the project iMERA-Plus according to the Grant Agreement No. 217257 between the European Commission and the European Association of National Metrology Institutes. The aim of the project is to develop methods for the direct measurement of the absorbed dose to water and to extend the use of this reference quantity to brachytherapy dosimetry with an uncertainty on the dose delivered to the target volume less than 5% (k=1) at clinical level. The present project will potentially increase the accuracy and safety of brachytherapy to a level comparable to that typical of radiotherapy with external accelerator beams.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Standard calibration of ionization chambers used in radiation therapy dosimetry and evaluation of uncertainties

Background: Absolute dosimetry of external beam radiotherapy is carried out by the use of ionization chambers. These chambers must be calibrated at a standard dosimetry laboratory before any use in clinical dosimetry. The secondary standard dosimetry laboratory of Iran (SSDL) has the duty of calibrating the ionization chambers used in radiotherapy centers in Iran. Materials and Methods...

متن کامل

Calibration of iridium-192 source by ionization chamber for high dose rate brachytherapy

Background: The effectiveness and safety of brachytherapy treatment is mainly concerned with the calibration of sources and their traceability to internationally accepted Standards. Secondary Standard Dosimetry Laboratory (SSDL) does not offer calibration of ionization chambers with gamma-ray spectrum of high dose rate source 192Ir . This work has been carried out to calibrate the high dose rat...

متن کامل

A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for 192Ir HDR Sources

High dose rate brachytherapy (HDR) using 192Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR 192Ir brac...

متن کامل

Material-specific Conversion Factors for Different Solid Phantoms Used in the Dosimetry of Different Brachytherapy Sources

Introduction Based on Task Group No. 43 (TG-43U1) recommendations, water phantom is proposed as a reference phantom for the dosimetry of brachytherapy sources. The experimental determination of TG-43 parameters is usually performed in water-equivalent solid phantoms. The purpose of this study was to determine the conversion factors for equalizing solid phantoms to water. Materials and Methods T...

متن کامل

Investigation of dose distribution 252Cf Isotron brachytherapy source based on TG-43U1 protocol by Monte Carlo method.

Introduction: The commercial 252Cf sources are too large in size and clinical applications of neutron brachytherapy (NBT) are limited to a small number of intracavitary treatments of cervical cancers. Recently, under the Cooperative Research and Development Agreement (CRADA) with Isotron Inc., the Oak Ridge National Laboratory (ORNL) encapsulated a new medical 252Cf sources, c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009